Showing posts with label sleep. Show all posts
Showing posts with label sleep. Show all posts

27 September 2014

BMJ Study "Links" Benzodiazepine Anxiety And Related "Z-Class" Sleeping Medication Use To Increased Risk For Alzheimer's Disease

       Friday, 26 September 2014, NEW YORK, NEW YORK - The Ninth Amendment editorial board sincerely urges that readers not become unnerved nor anxious by the above heading to this post. Although the heading is accurate to its New York Times source which concerned readers may go to directly at any time via the link provided below the Ninth Amendment finds a few introductory words in order as literally millions of Americans suffer from anxiety and/or insomnia a great many of whom at some time(s) or even for quite extended periods of up to many years have taken or take one or more of the above two groups of drugs which together are known to the medical community as "sedative-hypnotics". The "benzo" primarily anxiety drugs include ones such as Xanax, Ativan, Valium and Klonopin which are of similar composition but differing periods of action. The "z-class" sleep medications include Ambien and Lunesta.
      The last thing the Ninth Amendment wants to do is make any readers anxious or lose sleep so please relax and allow us first to convey a few points. The above headline refers to a summary article in the New York Times describing a study by Canadian and French medical researchers recently published in the well-regarded British Medical Journal (BMJ). Because of the high degree of reader interest in this area the Times article so far has generated well over three hundred comments and counting in the digital edition.
       Although it is important for our interested readers to be aware of the content of this article (which itself links directly to the full study for those interested) because it could prove lucrative fodder for media hype the truth of the matter is that a great many of the commenters including physicians weighing in on the Times article make seemingly valid points calling into question several aspects of the study done on the basis of medical records rather than dedicated study participants which make any suggestion of a conclusion based on everything from the lack of value of information presented which did not contain dosage information to a lack of evidence of other factors which may have affected the "control group".
       One commenting M.D.,Ph.D. whose comment was the second published in the digital Times following the article went so far as to observe that "there is a fairly large scientific literature showing benzodiazepines reduce the deposition of amyloid as well protect from the toxicity of the abnormal protein. Thus there is substantial basis to believe that this class of medications might actually be protective from Alzheimer's. . . ." This statement is consistent with the observation by the physician chief editor in the Harvard Medical Newsletter a few years past that despite the recent large-scale demonization (largely among physicians who never had experienced ongoing severe anxiety or used them) of benzodiazepines especially in any longer-term use that his lifetime of medical practice experience showed that long-term and even lifetime use of this class of medications was indicated in some patients for whom they had meant a huge improvement in quality of life for persons who might otherwise forever be virtually immobilized or unable to interact with others and society overall without constant overwhelming anxiety.
       This extended to the seemingly incomprehensible math used to reach any conclusion other than one that was unproven and premature at best. None of the physicians commenting found the study to be persuasive of the assertion of any causal "link" as implied in the Times headline reflected above. At best they concluded the demonstrated relationship might be stretched to the limit as an "association".  Many also took the Times to task for publishing an article of such personal medical interest to so many readers on this topic which was written by one with no recognized nor noted medical credentials at all must less a physician specializing in this field.
       Many of these points are touched on in the Ninth Amendment's comment to the Times article published earlier today in the Times digital edition. It is followed immediately by a link to the article itself which includes the 300+ comments published as of this posting as well as incorporating a direct link to the full study as published in the BMJ.
       THE NINTH AMENDMENT CANNOT AND DOES NOT PROVIDE NOR PURPORT TO PROVIDE ANY MEDICAL ADVICE TO ANYONE AT ALL. READERS MUST SEEK ALL MEDICAL ADVICE FROM A PROPERLY LICENSED MEDICAL PROFESSIONAL WHICH THE NINTH AMENDMENT IS NOT.

Ninth Amendment New York Times Digital Published Comment:




BigMartin

 waronnothing 27 minutes ago

With all due respect if the New York Times wishes to publish a medical column which greatly concerns a vast portion of the population who are ill and often suffer relentlessly even to the point of incapacity to interact or even meaningfully function at all with no other effective treatment available in this country the Ninth Amendment log at www.waronnothing.blogspot.com (which has no formal medical training whatsoever) respectfully suggests that rather than having it authored by one with apparently no formal medical credentials at all much less being a physician yet herself describes the subject as "a study designed with particular care" lasting for years yet then attempts to summarize in a few brief paragraphs that the Times has made a rather poor choice of one with authority meaningfully to interpret and present the information before ending the scant piece with an ominous quote from a physician making the pithy comment essentially that "Hey it's your life if you want to end it prematurely in a tragic mental void to pop a few sleeping pills be my guest". This is unhelpful just the type of medical advice a patient presumably would run from but for their suffering if it sounds as if they might get a prescription and some relief now that in the United States if one wishes to practice medicine there seems little point in enduring medical training and associated staggering debt to get an M.D. when one can get a G.E.D. join the DEA and "practice" medicine with no license at all.

Ninth Amendment New York Times SUBMITTED Comment 2 :



BigMartin
 waronnothing 

The Ninth Amendment log at www.waronnothing.blogspot.com (which has no medical expertise whatsoever) weighs in again on observing that comments here appear to be "all over the map". This confirms our earlier concern that this medical summary overall is not very helpful and should be presented ideally by a physician recognized as specializing in this area such that more readers might be left with a better more consistent understanding of what the underlying study did or did not conclude with some reasonable degree of assurance of the causal relationship of these drugs if any to the onset or course of Alzheimers Disease. This charged topic clearly is a matter of some importance to much of the population. The apparent lack of authority and consistent understanding here then seems to be addressed by the practice akin to opening "forums" where the value of each contribution is basically anyone's guess. We suggest that the Times consider following up this piece by one who might give readers more assurance of what was learned and most importantly what practical use they might make of that information. This is probably most helpful for those suffering from the underlying conditions the drugs are meant to treat to a degree of severity and for such a duration that those who have not experienced such extreme symptoms may not comprehend that they may drive one mentally into a hopeless condition regardless of their predisposition to depression when there seems no viable relief in sight.

New York Times Article:


Copyright 2014 Martin P. All World Rights Expressly Reserved

23 September 2012

MORE BREAKING NEWS - Texas Idiot Governor Rick "Payback" Perry Plants BS "Lack of Sleep" and "Leg and Foot Hurt" Story Attempting Damage Control By "Worst Campaigner/Candidate in American Political History"

     Sunday, 23 September 2012, AUSTIN- The editorial staff and global bureaus of the Ninth Amendment are pleased to announce that the New York Times in its recital of Texas Idiot Governor Rick "Payback" Perry's latest news comes from a new free source of Texas news -- texastribune.com provided the Times had the commonsense to thoroughly vet its source before recommending it. Readers are reminded to avoid READING FREE NEW YORK TIMES CONTENT SIMPLY BY SETTING FREE FIREFOX BROWSERS TO "PRIVATE BROWSING". Some recent experience indicates that should this technique no longer reliably work and interrupt reading of the Times that the Times "Cadillac" paywall can also be and of course as always should never be easily circumvented in numerous other ways mostly basically involving deleting the URL (top address bar line leave only a character or few). The Ninth Amendment of course will inform loyal readers as necessary what exactly is necessary should readers not wish to search "bypass New York Times paywall" themselves to study this subject for purely intellectual reasons.
     Perry's now released excuse for his abysmal Presidential campaign performance was "lack of sleep" and a "leg that hurt" in which he plummeted reportedly from first place to last place in less than six months upon entering the race after again having won the Texas governorship for about the firfh time with the quickly broken promise not to run for President in a campaign funded as usual by a handful of out-of-state interests who profited enormously from doing dirty and polluting business in nearby Texas where Federal air control laws were completely unenforced. Texas' air is the dirtiest in the nation. Perry was sworn in for his most recent marathon term as Texas Governor while as usual out of state in New York with his wife and enormously expensive "security detail" to drum up tourism for Texas as he does often in Japan. (Perry's enormous security detail a few years back was unable to stop a coyote who Perry shot himself with a six-shooter kept in the back of his jogging shorts, thus becoming the first North American person ever to have been attacked by a coyote and furthermore killing it which he later re-stated was to "protect his dog".)
     A review of past posts in this Ninth Amendment log readily reveals that lifelong financial loser Idiot Governor Rick "Payback" Perry made any personal wealth from sweetheart deals mostly in an exclusive Texas rich community at the Bay of "Pigs", Texas where he presumably will go into exile at some point when he no longer is capable of putting any English words together. Perry's horrible record stretches back throughout the continuous time he has served as Governor after being Lieutenant Governor after former Texas moron Governor George "little shrub" Bush who as is known went on to become "President" by losing the popular and electoral votes to former Vice President Al Gore, in which position "little shrub" Bush now still believed to be in crack rehab nearly destroyed the United States with an unprecedented eight years of exclusively wrong and dangerous decisions.
     President Obama as is known has had to spend nearly his entire first Presidency term undoing the horrible mess in which "little shrub" Bush left the United States in disaster at home and hated abroad. Unfortunately Drone Murderer Obama with henchman Attorney General Eric ("like my Hitler mustache?") Holder has made a habit of making permanent most of the clearly unconstitutional acts of the Bush Administration which at least contained sunset provisions.
     Now back briefly to poor "sleep-deprived" and "my leg hurt, and, oh yeah, my foot, too" Perry. It is common knowledge that throughout his failure to follow in the footsteps of "little shrub" crackhead Bush and completely drive the United States to ruin that upon Perry stepping into Bush's restraining shoes as Texas Governor both made it plain that they hated each other's guts. Readers below are provided with the direct link to the Texas Idiot Governor Rick "Payback" Perry excuse article in the Times. After several years preceding the Presidential election of documenting Perry destroy Texas (as a quick search of past posts here with the sidebar "search function" will reveal) he has never made an intelligent statement or decision including his frequent ignored threats to "secede" from the United States. (Go ahead become Mexico's northernmost province again. Perry also rejects all federal funding except when he needs it for his puppetmaster business bosses.
     Unfortunately Texas is sharing this legacy through its school system from which an unparalleled number of students drop out before leaving high school so they can become prepared for the worst prison system in the nation which features such attributes as housing more inmates raped by other inmates than any other state and housing prisoners on death row, often put to death as many as two a day frequently not even meriting mention in the Texas media in numbers greater than all the other States combined, the United States, or any other country in the world, although hopefully texastribune.com (if it is not a Perry or related damage control front, why is it a dot-com and not dot-org?) will help remedy that and is available reportedly to hopefully most cautious participation from all.
     Texastribune.com what is the source of your funding, your purpose, your allegiances, affiliates, etc, your purpose, why are you a dot-com and why does the New York Times have nothing more to say about your alleged organization and who reports and writes your news? Why is your first "contribution" to the national media a Perry apology piece? Please disclose all your financial records without limitation under affidavit with penalty of perjury under the laws of the State of Texas and the United States of America? Answer up.
     Finally should one think their way out in Texas is community college in a state with money-starved state colleges and universities, forget it. The quality of the education of Texas students who do get into its lousy community colleges staffed by instructors who could not teach inner-city high school in other states (similar to the quality level of Texas doctors drawn there by laws which make it virtually impossible to sue them for malpractice which we ourselves have experienced) has been brought highly into question as after a couple years nearly half of Texas community college students are thrown out for being unable to read English at an eighth-grade level.
     The Ninth Amendment invites readers to follow the below link to the apparent damage control article of Texas Idiot Governor Rick "Payback" Perry who apart from as some say lost a Presidential campaign in "ten minutes" in a nationally televised debate (later commenting "sometimes you just step in it) was declared on CNN by James Carville after entering the race in a solid first place barely six months before to have been the "worst political campaigner/candidate in American political history"'.
     Perhaps given his penchant for prayer Perry may take a few moments to pray and complain to former President Franklin Delano Roosevelt, Jr. about his "physical problems".


http://www.nytimes.com/2012/09/23/us/how-rick-perry-lost-his-edge-in-bid-to-be-president.html?_r=0

Copyright 2012 Big M All World Rights Expressly Reserved